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128

PERGUNTAS & RESPOSTAS

EMD

- Edema Macular Diabético

5. Michell P, et al. The RESTORE study: ranibizumab monotherapy or combined

with laser versus laser monotherapy for diabetic macular edema. Ophthalmology.

2014;118(4):615-625.

6. Schmidt U et al. Three - year outcomes of individualized ranibizumab treatment in

patients with diabetic macular edema: The RESTORE extension study. Ophthalmology.

2014;121(4):1045-1053.

7.

DRCR.net

Protocol I: Elman MJ, Ayala A, Bressler, Diabetic Retinopathy Clinical

Research Network. Intravitreal ranibizumab for diabetic macular edema with prompt

versus deferred laser treatment: 5–year randomized trial result. Ophthalmology.

2015;122(2):375-381.

8. Prunt C, Fajnkuchen F, Mahmood S et al. Ranibizumab 0.5mg treat - and - extend regi-

men for diabetic macular edema: the RETAIN study. Br J Ophthalmol. 2016,100(6):787-

95.

9. VIVID/VISTA: Korobelnik JF, Do DV, Schmidt - Erfurth U, et al. Intravitreal a`ibercept for

diabetic macular edema. Ophthalmology. 2014;121(11):2247-2254.

10. Rajendram R, Fraser-Bell S, Kaines A, et al. A 2 year prospective randomized controlled

trial of intravitreal bevacizumab or laser therapy (BOLT) in the management of diabetic

macular edema: 24 - month data, Report 3. Arch Ophthalmol. 2012;130:972-979.

11. Wells JA, Glassman AR, Ayala AR, et al. DRCR net Protocol T: Diabetic Retinopathy Cli-

nical Research Network, A`ibercept, bevacizumab, or ranibizumab for diabetic macu-

lar edema. New Engl J Med. 2015;372:1193- 1203.

12. Lauer AK, Bressler NM, Edwards AR. DRCR net Protocol B. Arch Ophthalmol. 2011

Aug;129(8):1097-1099.

13. Boyer DS, Yoon YH, Belfort R Jr, et al. MEAD Study: Three - year, randomized, sham -

controlled trial of dexamethasone intravitreal implant in patients with diabetic macular

edema. Ophthalmology. 2014;121(10):1904-1914.

14. Campochiaro PA, Brown DM, Pearson A, et al. FAME Study Group. FAME Study: Long

- term bene%t of sustained - delivery `uocinolone acetonide vitreous inserts for diabetic

macular edema. Ophthalmology. 2011;118(4):626-635.

15. Gillies MC et al. Bevordex study: A randomized clinical trial of intravitreal bevacizumab

versus intravitreal dexamethasone for diabetic macular edema. Ophthalmology. 2014

Dec;121(12):2473-81.

16. DRCR net Protocol U, assessed Sept. 13, 2015: Short - term evaluation of combination

corticosteroid and anti - VEGF treatment for persistent central - involved diabetic macu-

lar edema following anti - VEGF therapy.